Medical marijuana has emerged as a promising alternative treatment for those managing epilepsy and seizure disorders. With more patients turning to cannabis for relief, understanding which strains may offer the most benefit has become increasingly important. In this guide, we take a deeper look at the science behind cannabis and seizures, explore the differences between cannabis types and strains, and help you navigate which options may work best for your needs.
Disclaimer: This article is for educational purposes only and does not constitute medical advice. Please consult a qualified healthcare professional before beginning or changing any treatment. Veriheal can help connect you with licensed physicians to explore medical marijuana as part of your care plan.
When discussing marijuana, people often use the terms “type” and “strain” interchangeably. However, they serve different purposes when evaluating cannabis for medical use.
Understanding both types and strains is essential when choosing cannabis for seizure management, as individual responses can vary widely depending on the unique chemical profile of each plant.
Epilepsy is a neurological disorder characterized by abnormal electrical activity in the brain, leading to seizures. These can manifest as convulsions, sensory disturbances, or altered consciousness. According to the Centers for Disease Control and Prevention (CDC), approximately 3.4 million people in the U.S. live with active epilepsy.
Standard treatment typically includes anti-seizure medications that stabilize electrical activity in the brain. However, about 30% of people with epilepsy do not respond well to traditional medications. For these individuals, alternative treatments like dietary therapy (e.g., the ketogenic diet), surgical interventions, or medical cannabis may be considered.
Research into cannabis for epilepsy has accelerated in recent years, especially after the FDA approved Epidiolex, a purified form of CBD. It is specifically used to treat Lennox-Gastaut syndrome and Dravet syndrome, two rare and severe forms of epilepsy.
CBD is thought to help regulate brain activity by interacting with the endocannabinoid system, a network of receptors that influence pain, mood, appetite, and neurological function. Studies suggest that CBD may reduce the frequency and intensity of seizures in some individuals, though results vary (Mukhtar et al., 2025).
THC, the psychoactive compound in marijuana, has also shown potential but can sometimes exacerbate seizures, especially in high doses. This makes CBD-dominant strains the preferred choice for many patients.
Yes. In most U.S. states where medical marijuana is legal, epilepsy and seizure disorders qualify as eligible conditions. As of now, 43 states allow cannabis use for treating epilepsy.
To get a medical marijuana card:
Veriheal offers easy access to licensed physicians who specialize in cannabis medicine. Our platform helps streamline the process so you can explore marijuana as part of your epilepsy management.
Clinical and anecdotal evidence suggests that cannabis—especially strains high in CBD—may help reduce seizure frequency and severity. A 2018 clinical trial published in the New England Journal of Medicine found that CBD significantly reduced the number of seizures in children with Dravet syndrome.
Another study in Epilepsy & Behavior examined patients in Oregon and found that eighty-seven percent of the participants used marijuana for the treatment of epilepsy, and 82% found it helpful (Kerr et al., 2019). While this approach may not be universally effective, it opens the door for personalized treatments based on specific strains and cannabinoid ratios.
Some of the most frequently recommended strains for seizure management include:
Disclaimer: Cannabis affects each individual differently. What works for one person may not work for another. Always consult with your doctor and a knowledgeable budtender to find the safest option for you.
Yes, marijuana can affect seizures. CBD has shown promise in reducing seizures, while high THC content may sometimes worsen them. It’s important to work with a medical professional to determine the best cannabinoid profile for your condition.
Strains high in CBD with minimal THC are often considered best for neurological conditions like epilepsy. Charlotte’s Web and Cannatonic are two popular options.
Prescription anti-seizure medications are typically the first line of defense. However, for some individuals, CBD-based treatments like Epidiolex or high-CBD cannabis strains may provide relief. Always consult with a neurologist or epilepsy specialist.
Some terpenes may play a supporting role. Linalool (also found in lavender) and myrcene have calming and sedative effects that may support seizure control. More research is needed to confirm their benefits for epilepsy.
Marijuana can influence brain function by interacting with the endocannabinoid system, which helps regulate mood, memory, pain, and neural activity. In some individuals, cannabinoids may offer neuroprotective and anti-inflammatory benefits.
Certain medications, recreational drugs, or even excessive THC can lower the seizure threshold. Common culprits include antidepressants, stimulants, and alcohol. Always consult a healthcare provider when adding cannabis to your treatment regimen.
Most patients with epilepsy respond better to CBD-dominant strains, which can be found in both Indica and Sativa varieties. However, Indicas are typically more calming and may be preferred for their soothing effects. Personal response varies, so it’s important to try strains under supervision.
Disclaimer: This article is for informational purposes only and does not constitute medical advice. Cannabis affects individuals differently, and misuse can result in increased seizure activity or other side effects. Always consult your doctor before starting any cannabis regimen. Veriheal can help connect you with licensed professionals to explore safe, effective options for seizure management.
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