Research on the effects of medical cannabis on blood pressure is still ongoing, but some studies suggest potential benefits through its vasodilatory and anti-inflammatory properties.
When used over time, medical cannabis may help lower blood pressure. However, it is not a cure or definitive treatment, as conclusive medical evidence is lacking; rather, cannabinoids may support long-term reductions in blood pressure levels.
The endocannabinoid system (ECS) has CB1 and CB2 receptors that modulate cell behavior when cannabinoids bind to them. This interaction can affect how constricted or relaxed blood vessels are, as well as inflammation, both of which influence blood pressure. When blood vessels widen, blood flows more easily, and blood pressure can decrease.
Beyond the ECS, receptors in the endocannabinoidome (eCBome) like PPAR, GPR-55, and TRPV1 also cause vasorelaxant effects. These targets can be triggered by normal cannabis constituents like THC, CBD, CBG, terpenes, and more.
However, research on cannabis and blood pressure levels is mixed based on time measure. Some studies suggest cannabidiol (CBD) may lower blood pressure, while others show that tetrahydrocannabinol (THC) causes a brief rise in systolic blood pressure and heart rate and may also lead to orthostatic hypotension, a drop in blood pressure when standing, due to reduced vascular resistance.
Over time, cannabinoids, including THC, generally have long-term, anti-inflammatory, and vasorelaxant effects that may lower blood pressure. They can also influence levels of blood pressure medications, giving caution to older patients who are at higher risk of falls.
Overall, cannabis’ impact on blood pressure levels varies based on cannabinoid type, dose, and individual response.
A licensed medical marijuana doctor can review your full medical and cardiovascular history to determine the best treatment options, provide a personalized recommendation, assess risks and potential drug interactions, guide appropriate dosage and consumption methods, and adjust when necessary.
In complicated or severe cases, it is best to consult with your cardiologist first before initiating cannabis treatment.
Getting a medical marijuana card does not typically help with accessing cannabis for heart health because cannabis is not an approved treatment for heart conditions. Related qualifying conditions, like chronic pain, may make you eligible for a card, but anyone with a heart condition is advised to inform their doctor in order to determine the safest and most appropriate treatment plan while minimizing potential risks.
There have been multiple studies on the effectiveness of medical marijuana on hypertension. Most are preclinical, but a few of these studies include:
Although some results are promising, hypertension is not a qualifying condition for medical marijuana, and patients must use it only under medical supervision.
Presently, CBD is the most promising cannabinoid for lowering blood pressure. However, there is no strong, conclusive evidence showing that medical cannabis is a safe, effective, and reliable treatment for hypertension.
If used, approach with caution under medical supervision, favoring low-THC or non-smoked forms, with regular monitoring of cannabis effects on blood circulation and cardiovascular health. If you are older or on blood pressure meds, cannabinoids can make BP meds feel stronger and may increase the risk of dizziness and falls.
Some research suggests that medical cannabis – particularly cannabinoids and terpenes – may help lower high blood pressure.
No, medical cannabis cannot replace blood pressure medications. Always consult a medical cannabis doctor before using medical marijuana for blood pressure.
CBD-rich, CBG-rich, or balanced (1:1) strains may promote relaxation and help lower blood pressure compared to high-THC strains.
No, a medical marijuana doctor cannot ‘prescribe’ for hypertension.
You cannot obtain a medical marijuana card solely for blood pressure, although related conditions may make you eligible.
Presently, hypertension alone does not qualify for a medical cannabis card, but related conditions might; platforms such as Marijuana Doctors can help you see a medical marijuana doctor online and assist with the online application.
Yes, hypotension may occur due to factors such as cannabinoid content, dosage, postural change, and individual physiology. Older persons or those on blood pressure meds should take caution and report any dizziness, fainting, or other lightheadedness right away.
Yes, that is why individuals with heart conditions need to consult a licensed medical cannabis doctor and cardiologist before using cannabis.
Dosage impact on blood pressure varies based on cannabinoid type, dose, frequency, and individual response.
Yes. After reviewing your medical history, a medical cannabis doctor may determine that medical cannabis could benefit you and recommend a personalized plan that likely includes lifestyle and dietary change (i.e., DASH diet, Mediterranean diet, diets rich in fruits and veggies, etc.).
Written by Chiagozie Ekemezie
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