Updated on April 2, 2020. Medical content reviewed by Dr. Joseph Rosado, MD, M.B.A, Chief Medical Officer
A Cannabinoid 2 receptor is a type of G-protein type receptor that was researched and studied in 1993 to find out its function in the brain. CB2 receptors are an essential component of the body’s endocannabinoid system (ECS). The ECS is comprised of a network consisting of endocannabinoid receptors which help the body support its homeostasis. Pain, appetite, sleep, motivation and reward center, metabolic activity and man other essential functions are accentuated by the cannabinoid 2 receptor.
CB2 receptors are present in those parts of the brain where there is an inflammation or any injury. CB2 is expressed in low levels under physiological conditions but under pathological conditions such as neuropathic brain stroke, brain trauma, neurodegenerative disease or even drug addiction they heal inflammation. This feature can help pharmaceutical CB2 to heal traumas and other vital brain injuries.
The reason that cannabis has such a profound effect on one’s body is that the cannabinoids it produces acts with the CB1 and CB2 receptors and creates a euphoric feeling of high. Cannabis has been shown to help manage many chronic conditions.
The human CB1 and CB2 receptors have around 43% of amino acid alikeness.CB2 has also possible remedial roles in the treatment of neurodegenerative dysfunctions such as Alzheimers. Surprisingly, changes in endocannabinoid levels have been noticed in almost all diseases that have affected humans.