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Cannabigerol Monomethyl Ether (CBGM)

The cannabis plant contains about 85 compounds called cannabinoids that activate receptors in your body and cause the health benefits patients get from medical marijuana. One of these cannabinoids is known as cannabigerol monomethyl ether (CBGM).

CBGM’s Traits

CBGM is a member of the cannabigerol (CBG) cannabinoid group. The cannabinoids in the CBG group have similar molecular structures to CBG, meaning they may have similar properties. Like most other minor cannabinoids, not much research has been conducted about CBGM, but we do know a little bit about it.

Cannabis plants from northeast Asia seem to have the highest amount of naturally-occurring CBGM, but they still have a low amount compared to other cannabinoids. Interestingly enough, these same plants have high levels of THC and low levels of CBD.

Scientists from Kyushu University in Japan discovered CBGM in 1968 after isolating it from a Japanese hemp strain called Minamioshihara No. 1. When using acid to separate compounds from cannabis, they found a pale yellow syrupy substance that turned out to be CBGM. The team also found it using methylation, or by adding methyl molecules.

What Makes CBGM Unique?

Out of all the cannabinoids in the CBG group, CBGM is one of the only two to be an ether compound. This means it has an oxygen atom bonded to two aryl or alkyl groups. Ether molecules resemble the molecules in alcohol or water.

Besides its molecular structure, we don’t know much about what sets CBGM apart from other cannabinoids and members of the CBG group. With further research, we can hopefully learn more about this compound’s potential.

How Can CBGM Relieve Health Issues?

The little research we have on CBGM focuses on its molecular structure and relation to other cannabinoids, so we don’t know much about its effects on the human body. It may have similar health benefits to CBG, but it could also have unique properties no other cannabinoid has. Even just a small difference in molecular structure can completely change how a compound affects you.

Think about these two examples to understand how many medical possibilities CBGM has:

  • CBD has a counterpart called CBDV that has a slightly different structure. Both compounds have similar effects, although CBDV especially helps with some symptoms.
  • THCV, a counterpart to THC, can have the opposite effect of THC when used in a certain It can also suppress a patient’s appetite, which no other cannabinoid can do.

Conditions You Can Treat With CBGM

Since we have such little information on CBGM’s effects on the human body, we can only guess what health conditions it can relieve. If it has comparable results to CBG, it could help patients with conditions like:

Keep Track of CBGM Research

To truly understand how CBGM can help patients, we need more research on its effects. If you’d like to know when breakthroughs related to CBGM happen, check our blog on a regular basis. We’ll let you know as soon as possible when scientists find out any new information.


This information is not provided by medical professionals and is intended only to complement, and not to replace or contradict, any health or medical advice or information provided by healthcare professionals. If you have any questions, please contact your doctor or other healthcare professional.

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