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Medical Marijuana Research: Cannabis and Crohn’s Disease

Medical Marijuana Research: Cannabis and Crohn’s Disease

Posted by Marijuana Doctors on 11/04/2010 in Medical Marijuana Research

Medical marijuana patients across the country use cannabis to combat symptoms of Crohn’s disease, a chronic autoimmune inflammatory bowel disease that affects digestion, causes severe pain, and in rare cases, can be life-threatening. An estimated 500,000 Americans suffer from Crohn’s disease, though the number is probably much higher due to undiagnosed or misdiagnosed cases. Crohn’s disease is one of the most commonly cited reasons cannabis patients get medical marijuana. It’s an approved condition in most medical marijuana states.

Numerous case reports and preclinical studies have demonstrated that cannabis is an effective medicine for Crohn’s disease and other gastrointestinal (GI) disorders. Here is a round up of a few prominent medical marijuana research studies regarding cannabis and Crohn’s disease and other GI disorders:

  • A 2005 study published in O’Shaughnessy’s found that cannabis alleviates symptoms of Crohn’s disease[1]
  • A 2005 study called Cannabinoids and the digestive tract[2] found that the cannabinoids found in marijuana represent a novel therapeutic target for the treatment of numerous GI disorders — including inflammatory bowel diseases, functional bowel diseases, gastro-oesophagael reflux conditions, secretory diarrhea, gastric ulcers, and colon cancer.
  • A 2006 study published in the Journal of Endocrinological[3] Investigation demonstrates that activation of the CB1 and CB2 cannabinoid receptors exert biological functions on the gastrointestinal tract.
  • And the Journal of Clinical Investigation published a study titled “The Endogenous Cannabinoid System Protects Against Colonic Inflammation,” which reports that medical marijuana is a powerful anti-inflammatory that “represents a promising therapeutic target for the treatment of intestinal disease conditions characterized by excessive inflammatory responses.”

If you or someone you love is afflicted with Crohn’s disease, medical marijuana may help. But you must first ensure you are in compliance with your state laws. In all medical marijuana states, the first step is to see a qualified medical marijuana doctor. Book an appointment today with MarijuanaDoctors.com

Read more about Crohn’s disease and marijuana.


[1] Jeff Hergenrather. 2005. Cannabis alleviates symptoms of Crohn’s Disease. O’Shaughnessy’s 2: 3.

[2] Izzo and Coutts. 2005. Cannabinoids and the digestive tract. Handbook of Experimental Pharmacology 168: 573-598.

[3] Massa and Monory. 2006. Endocannabinoids and the gastrointestinal tract. Journal of Endocrinological Investigation 29 (Suppl): 47-57.

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