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Medical Marijuana and Hemophilia A

What Is Hemophilia A?

Hemophilia A is the most common type of Hemophilia and is also often referred to as “classic” Hemophilia or factor VIII deficiency. The largely inherited bleeding disorder is caused by a lack of blood clotting factor VIII. The disease is caused by an inherited X-linked recessive trait, with the defective gene being located on the X chromosome. The vast majority of people who suffer from Hemophilia A are males. The reason for this is that females have two X chromosomes while males only have one. If a female is born with a defective factor VIII chromosome on one gene, she typically has the other X chromosome available to make sufficient factor VIII. Males, however, do not have a “spare” X chromosome. As a result, if a male is born with a defective factor VIII chromosome, he has no way to make sufficient factor VIII and, therefore, has Hemophilia A. Approximately one in 5,000 males born in the United States has Hemophilia A.

Hemophilia A can be considered mild, moderate or severe depending on the amount of clotting factor found in the blood of the individual. Excessive bleeding, such as nose bleeds, blood in stools, and prolonged or spontaneous bleeding, is the predominant symptom of Hemophilia A. Bleeding into the joints, which causes pain and swelling is also a common symptom of the disease as is bruising. As a result of the bleeding into the joints, Hemophilia A sufferers also commonly live with chronic pain from the joint damage.

Hemophilia A is the most common type of Hemophilia and is also often referred to as “classic” Hemophilia or factor VIII deficiency. The largely inherited bleeding disorder is caused by a lack of blood clotting factor VIII. The disease is caused by an inherited X-linked recessive trait, with the defective gene being located on the X chromosome. The vast majority of people who suffer from Hemophilia A are males. The reason for this is that females have two X chromosomes while males only have one. If a female is born with a defective factor VIII chromosome on one gene, she typically has the other X chromosome available to make sufficient factor VIII. Males, however, do not have a “spare” X chromosome. As a result, if a male is born with a defective factor VIII chromosome, he has no way to make sufficient factor VIII and, therefore, has Hemophilia A. Approximately one in 5,000 males born in the United States has Hemophilia A.

Hemophilia A can be considered mild, moderate or severe depending on the amount of clotting factor found in the blood of the individual. Excessive bleeding, such as nose bleeds, blood in stools, and prolonged or spontaneous bleeding, is the predominant symptom of Hemophilia A. Bleeding into the joints, which causes pain and swelling is also a common symptom of the disease as is bruising. As a result of the bleeding into the joints, Hemophilia A sufferers also commonly live with chronic pain from the joint damage.

Medical Marijuana and Hemophilia A

Narcotic pain relievers also come with negative side effective such as dependency and addition with long-term use. High levels of opiate based pain relievers can also cause breathing problems. Medical marijuana may be used as an alternative to traditional narcotic pain medications or in conjunction with them to reduce the dosage.
Medical Marijuana and Hemophilia A: Clinical Evidence
Medical marijuana has been used as an analgesic, or pain reliever, by cultures throughout the world for centuries. Along with its historical use as a pain reliever, recent clinical studies have confirmed that medical marijuana does work to reduce pain, control nausea and vomiting and stimulate the appetite. A recent study conducted by researchers at San Francisco General Hospital looked at the effects of a group of participants who suffered from chronic pain. One group smoked three marijuana cigarettes a day while the control group smoked a placebo. The group that was given real marijuana reported a 34 percent decrease in pain compared to only a 17 percent decrease in the control group. Another study conducted at the University of California looked at the interaction between medical marijuana and traditional opiate based pain medications. That study concluded that the addition of medical marijuana to a regimen of opiate based pain relievers reduced the pain levels by an average of 27 percent while also reducing the levels of opiates in the participant’s blood.
Medical marijuana can also work as an anti-inflammatory to help with the swelling around the joint of a Hemophilia A sufferer. Along with the THC that works as an analgesic, medical marijuana also contains Cannabidiol, or CBD. CBD has been shown in clinical studies to have important anti-inflammatory properties. Along with CBD, medical cannabis has been shown to reduce tissue inflammation as a result of the presence of the compound β-caryophyllene. Both CBD and β-caryophyllene can work together to combat the joint swelling that is often preMedical Marijuana and Hemophilia A

Medical Marijuana and Hemophilia A

Conventional treatment for Hemophilia A often includes NSAIDs aimed at combating the swelling often found in the joints as a result of the bleeding within the joints. Unfortunately, NSAIDs can cause some serious negative side-effects. Nausea, vomiting, diarrhea, constipation or loss of appetite can accompany the use of NSAIDs. With prolonged use, NSAIDs can cause serious damage to the liver or kidneys. Medical marijuana is a viable alternative to the use of NSAIDs for the reduction of inflammation. Medical marijuana contains properties that work as an anti-inflammatory without the negative side-effects of NSAIDs.

Narcotic pain relievers also come with negative side effective such as dependency and addition with long-term use. High levels of opiate based pain relievers can also cause breathing problems. Medical marijuana may be used as an alternative to traditional narcotic pain medications or in conjunction with them to reduce the dosage.

Medical Marijuana and Hemophilia A: Clinical Evidence

Medical marijuana has been used as an analgesic, or pain reliever, by cultures throughout the world for centuries. Along with its historical use as a pain reliever, recent clinical studies have confirmed that medical marijuana does work to reduce pain, control nausea and vomiting and stimulate the appetite. A recent study conducted by researchers at San Francisco General Hospital looked at the effects of a group of participants who suffered from chronic pain. One group smoked three marijuana cigarettes a day while the control group smoked a placebo. The group that was given real marijuana reported a 34 percent decrease in pain compared to only a 17 percent decrease in the control group. Another study conducted at the University of California looked at the interaction between medical marijuana and traditional opiate based pain medications. That study concluded that the addition of medical marijuana to a regimen of opiate based pain relievers reduced the pain levels by an average of 27 percent while also reducing the levels of opiates in the participant’s blood.

Medical marijuana can also work as an anti-inflammatory to help with the swelling around the joint of a Hemophilia A sufferer. Along with the THC that works as an analgesic, medical marijuana also contains Cannabidiol, or CBD. CBD has been shown in clinical studies to have important anti-inflammatory properties. Along with CBD, medical cannabis has been shown to reduce tissue inflammation as a result of the presence of the compound β-caryophyllene. Both CBD and β-caryophyllene can work together to combat the joint swelling that is often present in.

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