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Medical Marijuana and Chronic Inflammatory Demyelinating Polyneuropathy

What Is Chronic Inflammatory Demyelinating Polyneuropathy?

Chronic inflammatory demyelinating polyneuropathy (often referred to as CIDP) is an acquired immune-mediated inflammatory disorder of the peripheral nervous system. This particular medical condition is sometimes referred to as chronic relapsing polyneuropathy (abbreviated CRP) or chronic inflammatory demyelinating polyradiculoneuropathy because it involves the nerve roots. Chronic inflammatory demyelinating polyneuropathy is closely associated with Guillain-Barré syndrome, and is considered the chronic counterpart of that specific acute disease. Symptoms of this particular medical condition are similar to that of progressive inflammatory neuropathy.

Chronic inflammatory demyelinating polyneuropathy is believed to be due to immune cells (those that normally protect the body from foreign infection), in which these cells begin to incorrectly attack the nerves in the body instead. As a result of this unexpected attack, any of the affected nerves begin to fail in response time or begin to respond in a very weak manner. This delayed or non-existent response can cause numbing, tingling, pain, progressive muscle weakness, loss of deep tendon reflexes (areflexia), fatigue, and abnormal sensations.

Medical Marijuana and Chronic Inflammatory Demyelinating Polyneuropathy

Due to that fact that neuropathic pain is often refractory to conventional prescription remedies, sometimes an alternative treatment option such as marijuana is necessary. One compound in medical marijuana (E)-BCP (beta-caryophyllene), is an anti-inflammatory but doesn't affect the molecular receptor that makes you feel stoned.

Instead, this compound could help a condition such as chronic inflammatory demyelinating polyneuropathy because it activates only the CB2 receptor which plays a key role in alleviating inflammation. Inflammation is necessary for wounds and infections to heal. However, chronic inflammation can lead to a host of diseases, such as atherosclerosis, rheumatoid arthritis, and even cancer.

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