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Medical Marijuana and Neurofibromatosis

What Is Neurofibromatosis?

Neurofibromatosis (otherwise known as NF) is a medical condition that refers to a number of various inherited conditions which are clinically and genetically distinct in nature. Each of these inherited conditions carry a high risk of tumor formation, particularly in the region of the brain. As an autosomal dominant disorder, only one copy of the affected gene is needed for Neurofibromatosis to develop. If only one parent has neurofibromatosis, his or her children will have a fifty-fit chance of developing the condition as well within their lifetime. However, it should be noted that it is rarely the case that one person has the mutated gene twice, which would imply a one-hundred chance of their children developing Neurofibromatosis. There are currently three varying types of Neurofibromatosis:

Neurofibromatosis Type I: Which the nerve tissue grows tumors (neurofibromas) that may be benign and may cause serious damage by compressing nerves and other tissues.

Neurofibromatosis Type II: Which bilateral acoustic neuromas (tumors of the vestibulocochlear nerve or cranial nerve 8 (CN VIII) also known as schwannoma) develop, often leading to hearing loss.

Schwannomatosis: Which painful schwannomas develop on cranial, spinal and peripheral nerves.

Medical Marijuana and Neurofibromatosis

The overall severity in affected individuals who have Neurofibromatosis can vary greatly, which sometimes may be due to variable expressivity. Approximately half of all Neurofibromatosis cases are due to de novo mutations and no other affected family members are seen. Typically this affects males and females equally, but some individuals may have mosaic Neurofibromatosis, which means some but not all cells of the body carry the mutation.

As a bona fide alternative treatment option, medical marijuana has been proven remedy for patients who seek pain relief time, anti-inflammatory effects and the treatment of Neurofibromatosis. It is already known that marijuana can stimulate the appetite of patients, but researchers have learned that cannabinoids, in addition to having palliative benefits in cancer therapy, have been associated with anti-carcinogenic effects, which are responsible in preventing or delaying the development of cancer or tumor spread. Additionally, medical marijuana has been responsible for slowing tumor growth rates and shrinking them in size.

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